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Category	Prescription Drug	Strength	Quantity	Cost
Antibiotic	Amoxicillin Tetracycline Zithromax	500 mg 500 mg 250 mg	30 pills 30 pills 6 pack	$52 $50 $94

Amoxicillin

Amoxicillin is an antibiotic in the class of penicillin drugs. It fights bacteria in the body but has very little effect on virus infections like colds or flu. Amoxicillin treats many types of bacterial disease, such as tonsillitis, pneumonia, ear and skin infections, bronchitis, urinary infections and gonorrhea among others.

Tetracycline

Tetracycline is used to treat bacterial infection, including pneumonia and other respiratory tract infections, acne, infections of skin, genital or urinary systems. It also may be used as an alternative for the treatment of Lyme disease and for the treatment of anthrax (after inhalational exposure). Using tetracycline in the absence of a strongly suspected bacterial infection is unlikely to provide benefit and increases the risk of drug-resistant bacteria.

Zithromax

Zithromax ( azithromycin ) is used to treat many types of bacterial infection including bronchitis, pneumonia, tonsillitis, skin infections, ear infections and sexually transmitted diseases. Zithromax is the trade name for the antibiotic azithromycin.  Zithromax is not effective against viral infections such as the cold or flu.

Antibiotics are drugs that fight infection caused by bacteria. Specific antibiotics kill specific bacteria. However, not all infections are caused by bacteria. Viruses are also important causes of infection. Antibiotics are not effective against viral infections like the common cold or flu. Your health provider must diagnose the infection to decide if an antibiotic is necessary, and if so, which one is appropriate to use.

Some bacteria can defend themselves against antibiotics. These bacteria are referred to as antibiotic-resistant. Because of these resistant bacteria, some infectious diseases have become more difficult to treat. Each time we take an antibiotic, bacteria are killed, but resistant ones may be left to grow and multiply. Resistant bacteria do not respond to the antibiotics and continue to cause infection. The misuse of antibiotics increases the growth and spread of these resistant bacteria.

Amoxicillin

Amoxicillin is similar to ampicillin in its bactericidal action against susceptible organisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell wall mucopeptide. Amoxicillin has been shown to be active against most strains of the following microorganisms, both in vitro and in clinical infections.

Aerobic gram-positive microorganisms:
Enterococcus faecalis
Streptococcus pneumoniae
Streptococcus spp. (a- and b-hemolytic strains only)
Staphylococcus spp. (b-lactamase-negative strains only)
  Staphylococci which are susceptible to amoxicillin but resistant to methicillin
  or oxacillin should be considered as resistant to amoxicillin.

Aerobic gram-negative microorganisms:
Escherichia coli (b-lactamase-negative strains only)
Haemophilus influenzae (b-lactamase-negative strains only)
Neisseria gonorrhoeae (b-lactamase-negative strains only)
Proteus mirabilis (b-lactamase-negative strains only)

Helicobacter:
Helicobacter pylori

Tetracycline

Tetracycline is primarily bacteriostatic and is thought to exert an antimicrobial effect by the inhibition of protein synthesis. Tetracycline is indicated for infections caused by the following micro-organisms:

Rickettsiae:
Rocky Mountain spotted fever
typhus fever and the typhus group
Q fever, rickettsialpox and tick fevers

Mycoplasma pneumoniae (PPLO, Eaton Agent)
Agents of psittacosis and ornithosis
Agents of lymphogranuloma venereum and granuloma inguinale
The spirochetal agent of relapsing fever (Borrelia recurrentis)

Gram-negative micro-organisms:
Haemophilus ducreyi (chancroid)
Pasteurella pestis, Pasteurella tularensis
Bartonella bacilliformis, Bacteroides species
Vibrio comma and Vibrio fetus
Brucella species (in conjunction with streptomycin)

Because many strains of the following groups of micro-organisms have been shown to be resistant to tetracyclines, culture and susceptibility testing are recommended. Tetracycline is indicated for treatment of infections caused by the following gram-negative micro-organisms, when bacteriologic testing indicates appropriate susceptibility to the drug:

Escherichia coli
Enterobacter aerogenes (formerly Aerobacter aerogenes)
Shigella species
Mima species and Herellea species
Haemophilus influenzae (respiratory infections)
Klebsiella species (respiratory and urinary infections)

Tetracycline is indicated for treatment of infections caused by the following gram-positive micro-organisms when bacteriologic testing indicates appropriate susceptibility to the drug. Streptococcus species: Up to 44 percent of strains of Streptococcus pyogenes and 74 percent of Streptococcus faecalis have been found to be resistant to tetracycline drugs. Therefore, tetracyclines should not be used for streptococcal disease unless the organism has been demonstrated to be sensitive. For upper respiratory infections due to group A beta-hemolytic streptococci, penicillin is the usual drug of choice, including prophylaxis of rheumatic fever. Diplococcus pneumoniae, Staphylococcus aureus, skin and soft tissue infections. Tetracyclines are not the drugs of choice in the treatment of any type of staphylococcal infections.

When penicillin is contraindicated, tetracyclines are alternative drugs in the treatment of infections due to:

Neisseria gonorrhoeae
Treponema pallidum and Treponema pertenue (syphilis and yaws)
Listeria monocytogenes, Clostridium species
Bacillus anthracis
Fusobacterium fusiforme (Vincent's infection)
Actinomyces species

In acute intestinal amebiasis, the tetracyclines may be a useful adjunct to amebicides. In severe acne, the tetracyclines may be useful adjunctive therapy. Tetracycline HCl is indicated for the treatment of uncomplicated urethral, endocervical or rectal infections in adults caused by Chlamydia trachomatis. Tetracyclines are indicated in the treatment of trachoma, although the infectious agent is not always eliminated, as judged by immunofluorescence. Inclusion conjunctivitis may be treated with oral tetracyclines or with a combination of oral and topical agents.

Zithromax (azithromycin)

Zithromax (azithromycin) acts by binding to the 50S ribosomal subunit of susceptible microorganisms, interfering with microbial protein synthesis. Nucleic acid synthesis is not affected. Azithromycin is indicated for the treatment of adult patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below.

Acute Bacterial Exacerbations of Chronic Obstructive Pulmonary Disease: Due to Haemophilus influenzae, Moraxella catarrhalis, or Streptococcus pneumoniae.

Pharyngitis/Tonsillitis: Caused by Streptococcus pyogenes as an alternative to first-line therapy in individuals who cannot use first-line therapy. (Penicillin by the intramuscular route is the usual drug of choice in the treatment of Streptococcus pyogenes infection and the prophylaxis of rheumatic fever. Azithromycin is often effective in the eradication of susceptible strains of Streptococcus pyogenes from the nasopharynx. Because some strains are resistant to azithromycin, susceptibility tests should be performed when patients are treated with azithromycin. Data establishing efficacy of azithromycin in subsequent prevention of rheumatic fever are not available.)

Uncomplicated Skin and Skin Structure Infections: Due to Staphylococcus aureus, Streptococcus pyogenes, or Streptococcus agalactiae. Abscesses usually require surgical drainage.

Urethritis and Cervicitis: Due to Chlamydia trachomatis or Neisseria gonorrhoeae.

Genital Ulcer Disease: In men due to Haemophilus ducreyi (chancroid). Due to the small number of women included in clinical trials, the efficacy of azithromycin in the treatment of chancroid in women has not been established.

Community-Acquired Pneumonia: Due to Chlamydia pneumoniae, Haemophilus influenzae, Mycoplasma pneumoniae, or Streptococcus pneumoniae in patients appropriate for oral therapy.

NOTE: Azithromycin should not be used in patients with pneumonia who are judged to be inappropriate for oral therapy because of moderate to severe illness or risk factors such as any of the following:

Not indicated for patients with cystic fibrosis.
Not indicated for patients with nosocomially acquired infections.
Not indicated for patients with known or suspected bacteremia.
Not indicated for patients requiring hospitalization.
Not indicated for elderly or debilitated patients.
Not indicated for patients with significant underlying health problems that may compromise their ability to respond to their illness (including immunodeficiency or functional asplenia).

NOTE: Azithromycin, at the recommended dose, should not be relied upon to treat syphilis. Antimicrobial agents used in high doses for short periods of time to treat non-gonococcal urethritis may mask or delay the symptoms of incubating syphilis. All patients with sexually-transmitted urethritis or cervicitis should have a serologic test for syphilis and appropriate cultures for gonorrhea performed at the time of diagnosis. Appropriate antimicrobial therapy and follow-up tests for these diseases should be initiated if infection is confirmed.

Appropriate culture and susceptibility tests should be performed before treatment to determine the causative organism and its susceptibility to azithromycin. Therapy with azithromycin may be initiated before results of these tests are known; once the results become available, antimicrobial therapy should be adjusted accordingly.

Disclaimer

This drug information is for educational purposes only. It is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.